METROGEL® Topical Gel is contraindicated in people that has a record of hypersensitivity to metronidazole, parabens, or other components with the formulation.
disulfiram boosts toxicity of metronidazole topical by lowering metabolism. Insignificant/Importance Unidentified. Enhanced CNS & cardiac toxicity with oral metronidazole and disulfiram; more unlikely to happen with topical administration due to lower absorption.
The incidence of individual adverse reactions weren't considerably distinctive involving The 2 regimens. Unless of course percentages are if not stipulated, the incidence of specific adverse reactions outlined under was less than one%:
In patients stabilized on relatively significant doses of lithium, short-term oral metronidazole therapy has become associated with elevation of serum lithium levels and, in several instances, indications of lithium toxicity.
In patients stabilized on relatively superior doses of lithium, shorter-time period oral metronidazole therapy has long been related to elevation of serum lithium stages and, in several cases, indications of lithium toxicity.
Prescription drugs which have step therapy affiliated with Every prescription. This restriction commonly demands that specified standards be achieved prior to approval for your prescription.
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This medication has been prescribed on your recent situation only. Usually do not utilize it later on for one more affliction Except if told to do so by your health care provider. A distinct medication can be required in Individuals conditions.
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METROGEL-VAGINAL affords negligible peak serum ranges and systemic exposure (AUCs) of metronidazole when compared to five hundred mg oral metro‑nidazole dosing. Although these reduce levels of exposure are not as likely to make the frequent reactions found with oral metronidazole, the possibility of these and various reactions cannot be excluded presently.
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Common dosage: Implement a skinny movie as soon as a day into the influenced areas. See offer insert for total prescribing Guidance.
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